Pope Leo celebrated his first Easter Mass as pontiff with a call Sunday to exercise hope against “the violence of war that kills and destroys,’’ saying “we need this song of hope today” as conflicts spread around the world.

With the US-Israeli war on Iran in its second month and Russia’s ongoing campaign in Ukraine, Leo has repeatedly called for a halt in hostilities.

In his Easter homily, the pope singled out those who wage war, abuse the weak and prioritize profits.

Leo, the first US-born pope, addressed the faithful from an open-air altar in St. Peter’s Square flanked with white roses, while the steps leading down to the piazza where the faithful gathered were filled with spring perennials, symbolically resonating with the pope’s message of hope.

The pontiff implored the faithful to keep their hope in the face of death, which lurks “in injustices, in partisan selfishness, in the oppression of the poor, in the lack of attention given to the most vulnerable.

“We see it in violence, in the wounds of the world, in the cry of pain that rises from every corner because of the abuses that crush the weakest among us, because of the idolatry of profit that plunders the earth’s resources, because of the violence of war that kills and destroys,” he said.

He quoted his predecessor Pope Francis in warning against falling into indifference in the face of “persistent injustice, evil, indifference and cruelty,” because “it is also true that in the midst of darkness, something new always springs to life and sooner or later produces fruit.”

He will later deliver the traditional “Urbi et Orbi” message — Latin for “to the city and the world.’’

Christians in the Holy Land were marking a subdued Easter

Traditional ceremonies at the Church of the Holy Sepulchre, revered by Christians as the traditional site of Jesus’ crucifixion and resurrection, were scaled back under an agreement with Israeli police.

Authorities have put limits on the sizes of public gatherings due to ongoing missile attacks.

The restrictions also dampened the recent Muslim holy month of Ramadan and Eid al-Fitr holiday, as well as the current weeklong Jewish festival of Passover.

On Sunday, the Jewish priestly blessing at the Western Wall — normally attended by tens of thousands — was limited to just 50 people.

The restrictions have strained relations between Israeli authorities and Christian leaders.

Police last week prevented two of the church’s top religious leaders, including Latin Patriarch Pierbattista Pizzaballa, from celebrating Palm Sunday at the Church of the Holy Sepulchre.

On Tuesday, the pope had expressed hope that the war could be finished before Easter.

Pope Leo XIV, carrying a tall, lit candle through a darkened and silent St. Peter’s Basilica, ushered in Christianity’s most joyous celebration with his first Easter vigil service as pontiff Saturday night, urging that Easter would bring harmony and peace to a world torn by wars.

Easter for Christians commemorates Christ’s triumph over death with his resurrection following his crucifixion.

Lighting the candle before he entered the basilica, the pope intoned: “The light of Christ who rises in glory.”

Candle bearers stopped to light candles of the congregants as they walked down the central aisle, spreading flickers of light through the dark basilica before the lights went up as the pope arrived at the baroque main altar, followed by cardinals dressed in white.

In his homily, Leo called sin “a heavy barrier that closes us off and separates us from God, seeking to kill his words of hope within us,’’ and likened it to the stone that had covered Jesus’ tomb — but which was found overturned, revealing Jesus’ resurrection.

Leo said that there are stones representing sins to be overturned today, some “so heavy and so closely guarded that they seem to be immovable.”

“Some weigh heavily on the human heart, such as mistrust, fear, selfishness and resentment; others stemming from these inner struggles, sever the bonds between us through war, injustice and the isolation of peoples and nations.

“Let us not allow ourselves to be paralyzed by them!” the pope said, calling on the faithful to make a commitment “so that the Easter gifts of harmony and peace may grow and flourish everywhere and always throughout the world.’’

With the U.S.-Israeli war on Iran in its second month and Russia’s ongoing campaign in Ukraine, Leo has repeatedly called for a halt in hostilities.

On Palm Sunday, he said that God doesn’t listen to the prayers of those who make war or cite God to justify their violence,

As is tradition, Leo baptized 10 adults from all over the world during the Mass.

During Leo’s first Holy Week, which is notoriously demanding, the pontiff carried the cross for the entire 14 stations during the Way of the Cross on Good Friday, the first time a pope has done so for decades.

On Holy Thursday, he washed the feet of 12 priests in the traditional Holy Thursday ritual, restoring a tradition his predecessor Pope Francis had broken by including laypeople and non-Christians.

On Sunday morning, Leo will celebrate an open-air Mass in St. Peter’s Square before delivering his Easter message and offer the traditional “Urbi et Orbi” message “to the city (of Rome) and the world,” which acts as a summary of the world’s woes.