How to defeat giant plant (Plant 43) in Resident Evil Requiem
The giant plant (Plant 43) in Resident Evil Requiem is one of the most unique bosses you will face during the final segment of the game, offering you a unique mix of challenge and tactics. It is based on the infamous Plant 42 and features a deadly attack, so it comes as no surprise that players are looking for easy ways to defeat it.
Here’s how you can defeat the giant plant (Plant 43) in Resident Evil Requiem.
Guide to defeat the giant plant (Plant 43) in Resident Evil Requiem

The giant plant (Plant 43) in Resident Evil Requiem is one of the final bosses you encounter on your way from the orphanage to the ARK, letting you warm up before the showdown. The plant-like creature has a central body with numerous nodes that extend outward to nip at you, dealing devastating damage.
Once you approach the giant plant (Plant 43) in Resident Evil Requiem, it is recommended to keep as much distance as you can while moving constantly. Do not stand in one location and offer yourself up as dinner for the plant. Now, focus on shooting at the large bud in the center. Avoid the tendrils, which will keep thrashing at you periodically.

You will find crates of green herbs and some ammunition for use if you are running low. Additionally, you will notice that there is a large white truck just below it. It is full of explosives, and you need to trigger a chain-reaction to reveal the explosives inside. Fire a few shots, and when the head of Plant 43 opens its mouth, throw in a grenade to deal devastating damage.

Follow this with repeated shots from your shotgun or Requiem. After a while, you will notice that it reacts violently, revealing a truck full of explosives just below. Aim for the truck and shoot it to set off a massive explosion that will set the plant on fire and ultimately kill it. It is recommended to avoid standing too close to it and using the grenade trick to dispatch it immediately.
Eliminating the giant plant (Plant 43) in Resident Evil Requiem will clear the way for Leon to finally make his way to ARK and save Grace. This is the final segment of the search for Elpis, offering a series of engaging fights along the way.
Also read: Resident Evil Recap: The Timeline explored
Check out more Resident Evil Requiem articles:
Are you stuck on today’s Wordle? Our Wordle Solver will help you find the answer.
Edited by Sayendra Basu